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About CodonRX


NC State Research Lab
CodonRX Probiotic Supplement
Digestive System Diagram
Our Story

Science-Backed Wellness, Made Accessible

CodonRX® was founded to make high-quality, science-backed wellness more accessible. Our product is made with NCK2025™, a patented probiotic born from the pioneering microbiome science at North Carolina State University.

Specifically formulated to support digestive balance,* CodonRX® helps you maintain a consistent and comfortable daily routine as part of a healthy lifestyle.

Read more about the research behind CodonRX®

The Research Foundation

Where the Science Comes From

NC State's Food Science program is ranked among the top ten in the country — and for good reason. Its researchers have spent more than four decades building some of the most comprehensive knowledge in the world on Lactobacillus acidophilus, the parent strain behind CodonRX.

That research produced NCFM®, one of the most extensively studied probiotic strains in scientific literature, and the lineage from which NCK2025™ was engineered. The critical discovery that shaped NCK2025™: that lipoteichoic acid (LTA), a surface molecule carried by standard L. acidophilus strains, was signalling the immune system to treat the probiotic as a threat — triggering the very inflammation and discomfort conventional probiotics are meant to relieve.

The findings have been published in PNAS and Immunotherapy. The solution is protected by two US patents. NCK2025™ is what happens when four decades of university research identifies exactly what to remove — and removes it.*

40+ Years of Research L. acidophilus studies at NC State
#9 Nationally Ranked Food Science program in the US
2 US Patents Protecting the NCK2025™ strain
2 Peer-Reviewed Journals PNAS & Immunotherapy

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Rodolphe Barrangou, Ph.D.
"

Our labs at NC State spent years researching and developing the anti-inflammatory properties of CodonRX.* It's rare for patented research to evolve into a real-world product that enhances quality of life. I'm thrilled to see CodonRX reach the market and hopeful that it will make a meaningful difference in consumer's health.


Rodolphe Barrangou, Ph.D. Inventor of CRISPR Gene Editing Technology
Distinguished Professor of Food, Bioprocessing and Nutritional Sciences
North Carolina State University

What Makes Us Unique

01 — Patented Formula

U.S. Patent Nos. 9,340,792 & 9,980,992

Our proprietary formulation is protected under internationally recognized patents developed at North Carolina State University, reflecting a focused, research-driven approach to long-term gut wellness.

02 — Scientifically Driven

Rooted in Microbiome Research

CodonRX® leverages deep insights from microbiome science, emphasizing digestive balance* as a core pillar of your consistent daily routine.

03 — Quality You Can Trust

USA-Made. Independently Tested.

Manufactured in the USA under strict quality standards, each batch is independently tested for potency and purity. CodonRX® is vegan and free from gluten, dairy, soy, nuts, and shellfish.

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