Why Most Probiotics Don’t Work for IBS — And How CodonRX Is Different

If you’ve ever taken a probiotic that seemed to help at first—only to have your symptoms return or worsen days later—you’re not alone.

It turns out, there’s a reason many probiotics provide only short-term relief for people with IBS or digestive sensitivities. And understanding that reason is exactly what led to the science behind CodonRX®.

The Problem with Most Probiotics? Hidden Inflammation.

Most probiotics on the market, no matter the strain, share a common feature: a fatty acid chain on their surface known as Lipoteichoic Acid (LTA). While this compound is naturally occurring, it’s been shown in studies to trigger inflammation in both the small and large intestines.

That’s right—even “good bacteria” can irritate the gut lining if LTA is present. This inflammation can quietly undo many of the benefits the probiotic is meant to provide, especially for people dealing with IBS, bloating, diarrhea, or constipation.

The CodonRX® Difference: Targeting Inflammation at the Source

CodonRX® is different. Our patented strain is engineered with LTA removed—a unique innovation supported by patents (USPTO #9,340,792 and #9,980,992). Without LTA, CodonRX can deliver its probiotic benefits without triggering inflammatory responses in the gut.

Even more importantly, clinical studies have shown that this LTA-free formulation doesn't just avoid inflammation—it helps reverse it. The probiotic acts as a traffic light, signaling the body to reduce pro-inflammatory activity and increase the production of anti-inflammatory molecules.

This means a calmer, more balanced digestive environment—and a better chance at lasting symptom relief.

How Inflammation Affects IBS Symptoms

IBS is a complex condition, but inflammation plays a major role in many of its hallmark symptoms. Here’s how:

• Diarrhea: Inflammation can damage the gut lining, impairing its ability to absorb water. The result? Urgent, watery bowel movements.
• Constipation: Inflamed intestines may contract abnormally, slowing digestion and causing cramping or painful bloating.
• Abdominal pain and bloating: Imbalance in the gut microbiome, fueled by inflammation, can lead to bacterial overgrowth and excess gas.

By addressing inflammation at the root, CodonRX® helps restore healthy gut function—supporting smoother digestion, more regular bowel movements, and reduced bloating.

Designed for People Who Haven’t Found Relief—Yet

CodonRX® isn’t just another shelf probiotic. It’s a new approach grounded in science and developed for people who’ve tried everything else. Our formulation goes beyond balancing gut bacteria: it actively reduces inflammation to help you feel better from the inside out.

If you’ve been managing IBS-like symptoms or struggling with inconsistent digestion, you may not need more probiotics—you may need the right one.

Experience the CodonRX® Difference Today

Take the first step toward real, lasting relief. Visit CodonRX.com to learn more or order your first carton.