Our Story From Life to Lab
Jun 19th 2025
For decades, the answer to gut health seemed simple: just add more "good bacteria." Yet for millions of people dealing with the daily frustrations of chronic bloating, gas, and irregular bowels, that answer was rarely enough. The relief promised by countless yogurts and generic probiotic supplements often fell short, leaving them to wonder why.
Microbiologists at North Carolina State University’s renowned food microbiology lab discovered the answer wasn’t a new blend, but a smarter, more targeted probiotic. Instead of just adding “good bacteria,” the team at Prof. Rodolphe Barrangou’s lab spent years developing a new strain called NCK2025™ that does one thing exceptionally well – target and reduce inflammation in the gut lining.
From this, CodonRX® was born. It was the result of decades of research by leading scientists in food microbiology. CodonRX® is the direct result of their dedicated scientific journey, created to offer real relief for those who need it most.
The Problem with "More"
Simply adding more "good bacteria" often isn't enough for lasting relief from persistent symptoms. The real issue is frequently chronic gut irritation that keeps your system feeling agitated and out of sync, leading to painful bloating, gas, and unpredictability.
Nearly all probiotics have a surface irritant called LTA. For many people it's harmless, but if you have a sensitive gut or IBS, it can act like an "alarm bell"—bringing only temporary relief or even making things worse.
Asking a Better Question
The scientists at NC State decided to ask a different question. Instead of asking, "How can we add more bacteria?" they asked, "How can we create a bacterium that actively calms the gut?"
This question led them down a path of precision science. They focused on a well-known and trusted probiotic, Lactobacillus acidophilus, and examined its structure at a molecular level. They identified a specific component on the bacterium’s surface—lipoteichoic acid (LTA)—that can sometimes be recognized by the immune system as an alert signal, potentially contributing to inflammation in sensitive individuals.
Their breakthrough idea was revolutionary: What if they could engineer a probiotic strain without this trigger?
NCK2025™: A Breakthrough in Precision Probiotics
After years of dedicated work, the research team successfully developed NCK2025™. This patented strain is a version of Lactobacillus acidophilus without the LTA alarm bell.
This single, crucial modification allows NCK2025™ to act with a purpose:
- It avoids triggering the alarm: Without the LTA component, NCK2025™ can work quietly in the gut without alerting the immune system.
- It promotes a calming response: Studies on the NCK2025™ strain have shown that it helps the body increase its own production of anti-inflammatory signals, actively helping to soothe the gut lining.
This wasn't about chance; it was about design. The result is a probiotic that doesn't just add to the population of good bacteria but fundamentally changes the environment to one of calm and balance.
Our Promise: Science-First Relief
CodonRX® exists today because of this unwavering commitment to scientific discovery. Every capsule contains the precision-engineered NCK2025™ strain, bringing decades of university research directly to you.
We believe that for those who have been let down by other solutions, the answer lies not in marketing trends, but in credible, peer-reviewed science. Our story began in a lab, and it continues with every person who finally finds the comfort and relief they deserve.
This allows CodonRX® to work differently. It can help soothe your gut and restore its natural harmony, offering a real chance at lasting comfort. Don't just get more probiotics. Get the right one.